IRON: AN ESSENTIAL NUTRIENT, A GLOBAL CHALLENGE
Iron is an essential mineral involved in numerous vital functions, including oxygen transportation, energy production, DNA synthesis, and support for the immune system, muscles, and brain. Despite its magnitude, iron deficiency remains the most widespread nutritional deficiency worldwide, oftentimes silent but with significant effects such as fatigue, shortness of breath, and cognitive difficulties.
We address this still under-recognized need with innovative nutritional solutions designed to optimize iron absorption while respecting human physiology. Even a mild iron deficiency can have a profound impact, and we are committed to making a difference.
The issues with conventional iron-based products
Conventional iron-based products, generally prescribed to manage iron deficiency and its anaemia, pose significant challenges. These products typically consist of inorganic ferric salts, such as ferrous sulphate or ferrous fumarate, that are poorly absorbed and are associated to gastrointestinal side effects, including constipation, diarrhoea and abdominal discomforts. Moreover, the presence of unabsorbed inside of the intestinal lumen can exacerbate mucosal inflammation and damage in patients with preexisting conditions.
Another issue to consider is the impact these products have on iron homeostasis. Differently to dietary iron, which undergoes finely regulated absorption and use, typical iron-based products often provide a sudden surge of iron into the body, bypassing physiological control mechanisms. This overload of iron can overwhelm the body’s capacity to control absorption and storage, leading to potential imbalances.
Additionally, the poor solubility of many conventional formulations can result in a high concentration of unabsorbed iron within the gastrointestinal tract which can then trigger oxidative stress, inflammation and damages to the gut mucosa, further compromising the body’s ability to efficiently regulate iron levels.
Consequently, while iron supplementation is crucial to address deficiencies, it is imperative to consider the limits of traditional iron sources and explore alternative supplementation strategies that align more closely with the body’s natural regulatory processes.